Maria was born in the Soviet Union, also the daughter of Olga Anisimova and Konsantin Anisimov. In 1998, when she was ten years old, her parents moved from Russia to the United States. Three years later, she became a big sister, when Amanda was born.

Amanda Anisimova booked her place in a maiden Grand Slam final after defeating World No. 1 Aryna Sabalenka in an epic semifinal clash at the 2025 Wimbledon.

Anisimova is 23 years old and stands 5-foot-11. She was born in 2001 to Russian parents Olga and Konstantin. Her parents moved to the United States in 1998, before Amanda was born in Freehold Township. The family moved to Florida when she was 3. Amanda also has an older sister named Maria, who played tennis at the University of Pennsylvania.