Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

"Where do new genes come from?" is a long-standing question in genetics and evolutionary biology. A new study from researchers at the University of California, Davis, published Jan. 23 in Science ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

Extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going—elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat ...

Oryza sativa is the most common type of rice used as a food crop. [C T Johansson [CC BY 3.0], via Wikimedia Commons] A team led by scientists from the University of Chicago (UChicago) has published a ...

In an unprecedented pan-cancer analysis of whole genomes, researchers at the Ontario Institute for Cancer Research (OICR) have discovered new regions of non-coding DNA that, when altered, may lead to ...

Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...