For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives.

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

According to the results of the early study, published simultaneously in the New England Journal of Medicine, 92% of patients who received only an immune-based treatment to help their own immune ...

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows. Led by ...

In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of the most promising approaches, known as immune checkpoint blockade, works by ...

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and ...

The findings were published in the journal Cell. The research was led by Leonie Uhl, Amel Aziba, and Sinah Löbbert, working with colleagues from the University of Würzburg (JMU), Massachusetts ...

Cancer immunotherapy has already transformed treatment for some patients, yet too often the body’s defenders stall out before they can finish the job. A wave of new research is now converging on a ...

Researchers at the University of California San Diego have discovered a promising new treatment approach for pancreatic ...

“Many confounding factors in real life—including lifestyle, UV exposure, occupational hazards, and immune status—can ...

Following on from their breakthrough human trial that successfully reprogrammed the immune system to overpower glioblastoma, an aggressive brain tumor, the same scientists have now further developed ...