The FDA’s new draft guidance on Bayesian methodology signals a shift toward more flexible, data-driven clinical trial designs, enabling sponsors to use prior data and adaptive approaches to improve ...

Bayesian methods have emerged as a pivotal framework in the design and analysis of clinical trials, offering a systematic approach for updating evidence as new data become available. By utilising ...

Updated guidance on vascular cognitive impairment emphasizes executive function and processing speed, endorses brief, ...

A Lupus Foundation of America (LFA) study released at the 2018 American College of Rheumatology (ACR) Annual Scientific Meeting supports using more novel analytic approaches to deal with the common ...

Findings support a groundbreaking approach in which naloxone (Narcan) enables complete transition from fentanyl to buprenorphine within one hour PORTLAND, Ore., Sept. 29, 2022 /PRNewswire/ -- As the U ...

Innovative statistical method helps determine ideal threshold times in restricted mean survival time analyses. The restricted mean survival time (RMST) analysis technique was introduced in health care ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

Pennington Biomedical Research Center hosted the NIDDK Clinical Methods for Nutrition and Obesity Research Course, an intensive four-day training program designed to equip postdoctoral fellows, ...

Infectious lower respiratory diseases and diarrheal diseases are top causes of deaths worldwide, accounting for 4.1 million deaths in 2019. The current COVID-19 pandemic is yet another reminder about ...

Decentralized clinical trials involve a combination of participant-centered design with innovative technologies. Decentralized clinical trials can either be fully remote or adopt a hybrid approach ...