Case-cohort study designs represent a cost-effective and efficient strategy for analysing time-to-event data, particularly when the event of interest is rare. By selecting a random subcohort along ...

Objective To characterise the risk of subsequent primary non-keratinocyte skin cancers (NKSCs) among adult-onset cancer survivors. Design Data analysis of this population-based cohort study was ...

Background Aortic stenosis (AS) frequently coexists with heart failure (HF), but its prevalence, prognostic impact and management across the full HF spectrum remain incompletely characterised. Methods ...

One of the world's most extensive birth cohorts is now entering later adulthood. At the University of Oulu in Finland, the ...

Objective To estimate the dose–response associations between non-occupational physical activity and several chronic disease and mortality outcomes in the general adult population. Design Systematic ...

Objectives We explored whether a spike in running distance during a single session or over 1 week, compared with the preceding period, was associated with increased risk of running-related overuse ...

A landmark German study finds that mRNA COVID-19 vaccination during the first trimester does not increase the risk of major congenital disabilities, offering crucial reassurance for expectant parents ...