This study introduces a penalized B-spline approach for estimating smooth curves, incorporating a total variation penalty to balance flexibility and interpretability. By leveraging group penalties and ...

Electrical property tomography (EPT) is a noninvasive method that uses magnetic resonance imaging (MRI) to estimate the conductivity and permittivity of tissues, and hence, can be used as a biomarker.

Choosing the right curve fit model is essential for revealing key data features, such as rate of change, asymptotes, and EC 50 /IC 50 values. The best model is the one that most faithfully reflects ...