A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...
RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...
The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound consequences for health and disease.DNA transcription is ...
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Pressing pause on DNA transcription: Imaging technique reveals what happens at the atomic level
A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural biologists at RIKEN. This could inform the development of new therapies.
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...
When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...
What determines a cell’s identity isn’t the genes within but how they’re used. To read and interpret this genetic material, cells rely on transcription factors. These proteins bind to specific regions ...
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