A dose-response curve is the graphical representation of a dose-response relationship, the magnitude of response of an organism from exposure to drugs and chemical interactors. Usually, dose is ...

Please provide your email address to receive an email when new articles are posted on . Until the last decade, efforts to develop a therapy that successfully targeted the KRAS mutation had been futile ...

Many oral drugs show a high variability in pharmacokinetic exposure, and, for drugs with exposure related to efficacy, therapeutic drug monitoring can help optimize exposure in individual patients.

Objective To estimate the dose–response associations between non-occupational physical activity and several chronic disease and mortality outcomes in the general adult population. Design Systematic ...

Correspondence to Dr Parco M. Siu, The University of Hong Kong, Hong Kong 999077, Hong Kong; pmsiu{at}hku.hk Objective To determine and compare the dose–response effects of exercise and caloric ...