Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...
In the world of gene-expression profiling, microarrays reign, but they are not without drawbacks. Microarrays have trouble with low-abundance transcripts and unidentified genes, for instance.
Small cell lung cancer (SCLC) remains a challenging cancer type to treat effectively. While patients initially respond to chemotherapy and immunotherapies, the disease almost always returns, often ...
Breast Cancer Index re-stratifies 21-gene assay risk groups for late distant recurrence and extended endocrine therapy benefit: Results from the BCI Registry Study. This is an ASCO Meeting Abstract ...
DNA profiling technologies are rapidly advancing, creating the potential to identify individuals involved in making, packing and transporting illegal capsules by analyzing the exterior of the illicit ...
PTEN is a tumour suppressor that may act by de-phosphorylating another signaling molecule, phosphatidyl inositol (PI) 3-kinase. In the November 6 Proceedings of the National Academy of Science, Javor ...
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