CRISPR promises revolutionary cures, but its edits aren’t always perfect. To tackle hidden risks, UC San Diego researchers developed the ICP system, which fingerprints genetic edits and shows how they ...
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Web-based tool improves CRISPR accuracy by identifying off-target effects across genetic variations
Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause ...
Understanding the genetic mechanisms linking genome variations, such as single-nucleotide polymorphisms (SNPs), to phenotypes is challenging. Quantitative trait loci (QTLs) are genomic loci that ...
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