How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

This work delineates how Setd2-mediated epigenetic reprogramming overcomes developmental barriers in cloned embryos. Comparative analysis revealed that SCNT embryos exhibit excessive H3K4me3 and ...

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

Patients identified as having a Janus kinase inhibitor responder profile were much more likely to respond positively to the class of atopic dermatitis therapies. Scientists have identified gene ...