A new review in Cell Division finds that the long non-coding RNA LINC01140 acts as an oncogene in some cancers and a tumor ...
A new review consolidates reported expression patterns, mechanisms, and clinical potential of the long noncoding RNA SNHG4 ...
Macrophages are considered the "scavenger cells" of the immune system, but some pathogens exploit these very cells as hiding places. Researchers from the Helmholtz Institute for RNA-based Infection ...
Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its ...
When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...
In a groundbreaking peer-reviewed review article, researchers have uncovered compelling evidence that long noncoding RNAs - molecules once dismissed as "junk DNA" - may hold the key to revolutionizing ...
A study has shown that a type of non-coding RNA molecule could play a role in the development of skin diseases—like eczema or psoriasis—and highlights an important molecular mechanism for driving ...
When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in ...
A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell — a new approach to drug discovery that has already yielded some promising ...