Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

ARHGAP11B -- this complex name is given to a gene that is unique to humans and plays an essential role in the development of the neocortex. The neocortex is the part of the brain to which we owe our ...

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein ...

To build the neocortex, a brain area involved in higher cognitive functions, stem cells produce billions of neurons of various types. In a Science study, neuroscientists from Switzerland, Belgium, and ...

The question of what makes modern humans unique has long been a driving force for researchers. Comparisons with our closest relatives, the Neandertals, therefore provide fascinating insights. The ...

A human-specific gene causes a larger neocortex in the common marmoset, a non-human primate. A human-specific gene causes a larger neocortex in the common marmoset, a non-human primate. The expansion ...

Dresden and Leipzig researchers find that stem cells in the developing brain of modern humans take longer to divide and make fewer errors when distributing their chromosomes to their daughter cells, ...