In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that gives rise to dopaminergic neurons, the primary neurons affected ...

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

For decades, scientists have been searching for better ways to treat diseases that slowly destroy the brain. Conditions such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease ...

A new study in zebrafish reveals that the gene nexmifb—a paralog of the human neurodevelopmental gene NEXMIF—plays a critical role in spinal motor neuron development by modulating the axon guidance ...

To better model how neurons fire and interact with glia, some scientists place the cells into a brain or grow them in an organoid. Others have produced little spheres of human neural tissue by ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

A baby's neuronal development can be compromised by infections in utero Source: Peter Oslanec/Unsplash It goes without saying that the health of a pregnant mother and the conditions inside the womb ...

Leuven, 7 August 2024—The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU ...