Ongoing elimination efforts have altered the global distribution of Onchocerca volvulus, the agent of river blindness, and further population restructuring is expected as efforts continue. Therefore, ...

Previous ultrastructural studies on various microfilariae have suggested the presence of a trilaminar membrane at the parasite cuticle. In the present report, the formation of the cuticle of ...

Despite decades of research, scientists have yet to pinpoint the exact cause of nodding syndrome (NS), a disabling disease affecting African children. A new report suggests that blackflies infected ...

This is a preview. Log in through your library . Abstract The effects of temperature on the development of Onchocerca volvulus in Simulium ochraceum, and on the vector's longevity were studied under ...

Recent reports of patients failing to respond to ivermectin, the standard drug for treating river blindness (onchocerciasis), have suggested the emergence of drug-resistant Onchocerca volvulus (the ...

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels. The Food and Drug Administration (FDA) has approved ...

The debilitating parasitic disease, onchocerciasis, is all but vanquished in one corner of Sudan, thanks to a community-wide health effort. A series of rodent experiments showed that even with ...

Tommy Leung does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Steven Williams’ laboratory focuses on research designed to elucidate the molecular biology of the parasites that cause Neglected Tropical Diseases—diseases that afflict the poorest billion people on ...