Business Wire

First Patient Recruited for Multi-Year Collaborative Primary Sclerosing Cholangitis (PSC) Pediatric Study Using Perspectum’s Imaging Technology to Help Predict Disease ...

SAN FRANCISCO--(BUSINESS WIRE)--Perspectum announced recruitment of the first patient in a multi-center collaborative study to characterize Primary Sclerosing Cholangitis in children, “Prospective ...
Nature

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Table 1 Association summary statistics across four newly associated PSC risk loci Figure 1: Odds ratios (and their 95% confidence intervals) for PSC, UC and CD across the six PSC-associated SNPs ...
ascopubs.org

Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer.

Phase I study of weekly outpatient paclitaxel and concurrent cranial irradiation in adults with astrocytomas. Thirty-four patients were treated with 53 cycles of PSC 833 and etoposide. Steady-state ...
ascopubs.org

Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC-833 in relapsed or refractory acute myelogenous leukemia.

Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer ...