Thrombocytopenia absent radius (TAR) affects the radius — the long, thin bone in the forearm — and platelet function. This defect commonly appears at birth or within the first few years of life.

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

The coronavirus disease-19 (COVID-19) pandemic that emerged in Wuhan, China, in late December 2019 spread rapidly throughout the world and has caused over 6.5 million deaths. The disease is caused by ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

A new study created a score to identify patients with platelet hyperreactivity and risk of related, future cardiovascular disease. Platelets are circulating cell fragments known to clump up and form ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...

In a recent study published in the Journal of Thrombosis and Haemostasis, researchers investigated the role of platelets in the adverse immune response against a coronavirus disease 2019 (COVID-19) ...

A team from Würzburg has fundamentally changed our understanding of platelet biology with a study published in Science. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only ...