The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

The design and construction of capital projects can be extremely complex. Uncertainty and risk add to this complexity and, as a result, many projects experience significant cost overruns and schedule ...

Probabilistic model checking and Markov decision processes (MDPs) form two interlinked branches of formal analysis for systems operating under uncertainty. These techniques offer a mathematical ...

Mechanistic process and product modeling turns data into knowledge that can be extrapolated with known confidence for design space characterization and risk assessment. Mechanistic modeling uses ...

You have probably used your math background if you have been playing with robots for awhile. However, unless you have been doing video processing, you may not have been able to take advantage of that ...

One of the key factors contributing to continuous safety improvement at nuclear power plants is a comprehensive safety assessment, factoring in insights from the probabilistic safety assessment to ...

A DARPA-funded processor start-up has made bold claims about a new kind of processor that computes using probabilities, rather than the traditional ones and zeroes of conventional processors. Lyric ...

Project Delivery Methods have expanded dramatically. The integration of design and construction on projects can reduce the project schedule and allow for construction and property management input ...