Two new options for making designer proteins made news in 2001—both from labs at Scripps Research Institute. Since 2001, Schimmel and Schultz have taken different directions with unnatural amino acids ...

There have been many attempts to classify proteins into groups of related molecules in terms of their primary, secondary and tertiary structure. An overview of these classification schemes is ...

Accurately and rapidly quantifying protein content is essential for modern biology, biochemistry, and biophysics laboratories worldwide. Researchers are focused on determining total protein content, ...

Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...

E3 ligases are enzymes that act as molecular "broker" by binding specific target proteins and coordinating the transfer of ubiquitin from an E2 enzyme. As an E3 ligase recognizes only a restricted set ...