Artificial intelligence (AI) is transforming how scientists understand proteins—these are working molecules that drive nearly every process in the human body, from cell growth and immune defense to ...

Today (September 21), the Lasker Foundation announced this year’s award winners. John Jumper, a computational biologist at DeepMind, and Demis Hassabis, cofounder and CEO at DeepMind, were awarded the ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...

The success of ChatGPT and its competitors is based on what’s termed emergent behaviors. These systems, called large language models (LLMs), weren’t trained to output natural-sounding language (or ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

Scientists from Scripps Research have uncovered new structures of transthyretin, a protein that moves important hormones like thyroxine through blood and spinal fluid. Misfolded versions of the ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Animated clip of SARS-CoV-2 fusing with a host cell. To see the full video, click on the image. Covid-19 begins when the SARS-CoV-2 virus first encounters cells in the upper airway that express a ...

Over the millennia, viruses have become excellent manipulators of biology. But there’s a lot that scientists don’t know about how viruses work, in part because they have relatively little insight into ...