Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information from ...

The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Which came first, nucleic acids or proteins? This question is molecular biology’s version of the “chicken-or-the-egg” riddle. Genes made of nucleic acids (DNA or RNA) contain the instructions for ...

A study finds that an RNA enzyme, or ribozyme, can evolve to produce complex RNAs efficiently but at the cost of synthesis accuracy. Key to the development of RNA-based life, which is thought to have ...

The growth and metastasis of solid tumors relies on the activities of polypeptide growth factors to recruit stromal tissue and expand the tumor mass. Pleiotrophin (PTN) is a secreted growth factor ...

RNAs have rapidly emerged as the key players in many fundamental biological processes, as well as the bridge to future medicine. The Yen laboratory is interested in the biology of RNA molecular ...

In the March 19 Proceedings of the National Academy of Sciences, Mohammed Kashani-Sabet and colleagues describe the use of plasmid-based ribozymes as functional genomics tools to unravel complex ...

RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...