The FDA approved the first generics of the direct oral anticoagulant rivaroxaban, the agency announced on Tuesday.

Two companies have received approved for a generic of the 2.5 mg tablet of anticoagulant rivaroxaban, which is used to reduce ...

For this understudied population, the findings may offer some reassurance as apixaban is already the most prescribed OAC in the general population of the U.S. and in people with H ...

Half of renally-cleared rivaroxaban is cleared as unchanged drug and half as inactive metabolites. ‡Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole ...

Rivaroxaban, on the other hand, is associated with an increased signal of harm. “What our analysis shows is that within the limitations of the studies that have been done, it does appear that the risk ...

Venous thromboembolism, comprising pulmonary embolism and deep vein thrombosis, is a common disease with considerable mortality and morbidity, such as post-thrombotic and post-pulmonary-embolism ...

A systematic review and meta-analysis of nine trials comparing non-vitamin K oral anticoagulants with low-dose aspirin revealed a link between rivaroxaban and higher rates of major bleeding and ...

In this randomized controlled trial, abelacimab led to significantly lower rates of major or clinically relevant nonmajor ...