The FDA has approved the first generic versions of Johnson & Johnson's big-selling anticoagulant Xarelto, which brought in ...

Rivaroxaban, on the other hand, is associated with an increased signal of harm. “What our analysis shows is that within the limitations of the studies that have been done, it does appear that the risk ...

The approval is only for the 2.5mg tablet. Xarelto is also available in 10mg, 15mg, and 20mg tablets, as well as an oral suspension (1mg/mL), to treat various conditions.

Image: Adobe Stock “For patients transitioning from aspirin to a NOAC, our findings suggest that apixaban and dabigatran may offer a safer bleeding profile compared to rivaroxaban,” Michael Ke ...

Half of renally-cleared rivaroxaban is cleared as unchanged drug and half as inactive metabolites. ‡Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole ...

Study: Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation. Image Credit: Lightspring / Shutterstock A recent study published in the New England Journal of Medicine evaluated ...