Seth Shipman is a magpie of biological innovation. He collects useful parts — from bacteria, nerve cells, reams of genetic data — and transforms them into tools that do amazing things.

Within bacterial cells, specialized immune systems known as retrons fend off viral attacks. But that's not all they can do. Scientists, including Seth Shipman, Ph.D., at Gladstone Institutes, have ...

"We wanted to push the boundaries of genomic technologies by engineering tools to help us study the true complexity of biology and disease," says Associate Investigator Seth Shipman, Ph.D., senior ...

Seth Shipman (right), Alejandro González-Delgado (left), and their colleagues at Gladstone Institutes closely examined never-before-tested retrons, bacterial defense systems that can be leveraged ...

A team of Harvard scientists led by geneticists Seth Shipman and Jeff Nivala has just developed a fascinating way to write chunks information into the genetic code of living, growing bacterial ...

Now, a team led by Dr. Seth Shipman at Gladstone Institutes engineered a biological recorder—dubbed Retro-Cascorder—that, like an old school camcorder, can capture a cell’s gene expression history on ...

The National Institutes of Health (NIH) has granted an NIH Director's New Innovator Award to Seth Shipman, PhD, assistant investigator at Gladstone Institutes. The award will support the ...

To avoid these problems, scientists at the Gladstone Institutes led by associate investigator Seth Shipman, PhD, have been developing a sleeker, retron-oriented approach.

For Seth Shipman, a bioengineer at Gladstone Institutes in San Francisco, California, leveraging these defenses has opened new technological possibilities for recording gene expression in cells.

Alejandro González-Delgado, Santiago C. Lopez, Matías Rojas-Montero, Chloe B. Fishman, Seth L. Shipman. Simultaneous multi-site editing of individual genomes using retron arrays.