A new review in the Journal of Translational Medicine argues that c-MET signaling shapes spatially confined, metabolically ...

Spatial multi-omics has rapidly become one of the most powerful lenses in modern biomedicine, allowing researchers to map ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Illumina's spatial transcriptomics offering is slated to provide analyses of millions of cells per experiment across a 50 mm by 15 mm imaging area. (Pixabay) Illumina is raising the curtain on its ...

Spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) are often framed as rivals, but they answer different questions about the same tissue. Single-cell RNA-seq resolves cell identity at ...

Tissue preparation is the step in spatial transcriptomics that can determine whether an experiment succeeds or fails before the sample ever reaches the instrument. Getting fixation, sectioning, and ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...