Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The ...

Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...

Researchers show how LGP2 binds viral RNA ends, moves along the strand, and helps MDA5 form filaments that amplify antiviral signaling. The findings clarify an early defense step and may inform ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

A study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science ...

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...

Zika virus (ZIKV) is a mosquito-borne orthoflavivirus that can cause birth defects, including microcephaly, a condition in which head and brain size are significantly reduced at birth. The collective ...

It starts quietly, a bite or a scratch, and by the time symptoms surface, it’s often too late. Rabies isn’t just a distant threat—it’s alive and present here in Alabama. Prevention remains critical, ...