Translocations occur in a proportion of couples affected by recurrent miscarriages. We describe two such families in which the underlying cause was a cryptic subtelomeric 11p;17p translocation ...

Second cancers following pediatric Hodgkin's disease. Translocation (1;19)+ patients were more likely than t(1;19)- patients to be 10 years of age or greater (P < .001) or CD10+ CD19+ CD34- (P < .0001 ...

When chromosomes break, trouble usually ensues; chromosome abnormalities are the single biggest cause of birth defects in humans. But a new study of translocations, in which two chromosomes swap ...

Somatic structural genome alterations such as changes in copy number or chromosomal rearrangements can promote genome instability and cancer development, and identification of these mutations is ...

Inside of each of your cells are thread-like structures made up of parts called chromosomes. These tightly wound threads are what people mean when they refer to your DNA. It’s a blueprint for cell ...