When it comes to lab tests, interpreting the clinical importance of an out-of-range result depends on how much experience a physician has, suggests research from the Johns Hopkins Children’s Center.

Consider a study to evaluate treatment A with a placebo in two or more groups of patients. If treatment A is beneficial to one group of patients and harmful to another, then we say that there is ...

Optimal critical values and times of intermediate testing points are determined to minimize expected sample size in a variety of situations. Two-stage and three-stage models are considered for a ...