The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the ...

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...

Researchers have found a small but powerful switch inside breast cancer cells that helps them survive stressful conditions.