Five years ago, Nobel laureate Carolyn Bertozzi, PhD, and her team described novel small RNA-glycan conjugates, glycosylated RNAs (glycoRNAs), on the cell surface. These small non-coding RNAs have ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular pathways. However, traditional single-cell ...

The role of RNAs keeps growing and growing. New research shows that cell surface RNAs are critical in neutrophil recruitment to inflammatory sites. These “glycoRNAs” on the cell surface of neutrophils ...

A metabolic enzyme studied for over seven decades has a hidden second function - it can unwind RNA and promote cell cycle ...