Any organism is a by-product of both its genetic makeup and the environment. To understand this in detail, we must first appreciate some basic genetic vocabulary and concepts. Here, we provide ...

Genotype–phenotype databases contain data on genetic variants and associated phenotypes. In medical contexts, such databases are focused on disease-causing mutations and resulting diseases or ...

For the majority of common human diseases, only a small fraction of the heritability can be attributed to known genetic variation. A widely held hypothesis is that the remaining heritability can be ...