The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

Immunoglobulins are central to shaping immune responses and are critical tools for probing biological mechanisms in biomedical research. However, selecting an inappropriate antibody isotype can lead ...

In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers (HCWs), emphasizing the IGHV1-69 ...

In a recent study published in Science Translational Medicine, researchers evaluated the differential humoral immune response to two coronavirus disease 2019 (COVID-19) vaccines - messenger ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

Antibodies—proteins that are produced by our immune system to protect us—are crucial for recognizing and getting rid of unwanted substances, or antigens, in our body. Although their role is universal, ...

Thyroid antibodies are cells the immune system forms in response to thyroid cells. They develop when the immune system mistakenly attacks thyroid cells and tissues. High levels can indicate an ...