The central dogma processes of DNA replication, transcription, and translation are responsible for the maintenance and expression of every gene in an organism. An orthogonal central dogma may insulate ...

Simply put, orthogonal validation uses additional methods that provide very different selectivity to the primary method to confirm or refute a finding. All methods are independent approaches that can ...

In many experimental situations the pertinent inferences are made on the basis of orthogonal contrasts among the treatment means (as in 2 n factorial experiments). In this setting a particularly ...