Researchers developed predictive models using routine clinical metrics to estimate pain modulation profiles in chronic pain.

Share on Pinterest A recent study used computational methods to identify novel compounds that activate receptors involved in pain modulation without sedation. Peter Dazeley/Getty Images Research on ...

Neuropathic pain, resulting from disturbances within the somatosensory system, affects millions worldwide, significantly ...

Please provide your email address to receive an email when new articles are posted on . The randomized, controlled, crossover study enrolled 20 healthy volunteers (mean age, 50 years; 50% women) and ...

This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...

It’s not all in your head, but your expectations can sway your perception of pain intensity. Information about expectations — the driver of the placebo effect — travels from the cortex to groups of ...

Classical conditioning can profoundly modify subsequent pain responses, but the mechanisms that drive this effect are unresolved. In pain-conditioning studies, cues are typically conditioned to ...

Pain is both a sensation and an affect. Affects are subjective reactions to sensations. That’s why the same stimulus can evoke excruciating pain in one person and mild discomfort in another. In this ...

A publication from Acta Pharmaceutica Sinica B discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a debilitating ...