CAMBRIDGE, MA -- Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

For patients with disorders such as autism and schizophrenia, mutations in the same gene could require different treatments, according to new research from Yale School of Medicine (YSM). Many ...

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, ...

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

More than 30 types of muscular dystrophy have been identified. They all cause problems with movement due to muscle protein defects caused by genetic mutations. Muscular dystrophy is a group of ...

Researchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences in the mutations that ...

When people donate blood, stem cells in the bone marrow make new blood cells to replace what was lost. This stress can drive the selection of certain clones—groups of blood cells with a slightly ...

New research suggests that frequent blood donation can trigger genetic changes that might protect certain stem cells from becoming cancerous. Reading time 3 minutes Your regular donation of blood ...