A first-in-human study suggests that tirzepatide modulates abnormal activity in the brain’s nucleus accumbens, reducing food cravings and inducing weight loss in severe obesity.

A rare intracranial brain-recording study revealed that tirzepatide, a GLP-1 and GIP receptor agonist, temporarily silences craving-related neural activity in a key reward circuit of the brain.

The study, published in Biological Psychiatry: Global Open Science, found the effect occurs in the paraventricular nucleus of ...

Deep Brain Stimulation (DBS) is an invasive treatment. Pairs of electrodes are surgically implanted in the brain and connected to a pulse generator placed under the skin on the chest. DBS-nbM delivers ...

A new clinical trial shows that deep brain stimulation (DBS) improved symptoms in half of adults with treatment-resistant depression, with one-third reaching remission.

Popular drugs for diabetes and weight loss, like Ozempic, Wegovy, and Mounjaro, can have profound impacts on the body, but what about the brain? These medicines are thought to broadly suppress ...

A BRAIN ‘pacemaker’ has helped treat half of severely depressed or anxious patients by correcting ‘bad brain signals’. Scientists say 34.6 per cent of people in the trial ...

Deep brain stimulation—implants in the brain that act as a kind of "pacemaker"—has led to clinical improvements in half of the participants with treatment-resistant severe depression in an open-label ...