Although the molecular machines that power ATP synthesis via trans-membrane proton gradients are well known, how the gradient is created in the first place is more mysterious. Now, a crystal structure ...

Use of proton pump inhibitors (PPIs) may spur progression to kidney failure in patients with chronic kidney disease (CKD), according to 2 nationwide Asian studies. In a study of 83,432 adults with ...

Sharma’s study examined the ATP synthase at an acidic state just below neutral on the pH scale. By examining ATP synthase in this way, the researchers uncovered several new insights into how the ...

Zhu KJ, Feng W, Ma XN, et al. Proton pump inhibitor use associated with an increased risk of gout: A population-based case-control study. Int J Rheum Dis. Published online July 20, 2023. doi:10. ...

In the late 1990s, some scientists hypothesized that the former food vacuole was still likely to carry a transmembrane channel protein called a proton pump. Proton pumps are highly versatile molecules ...

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into ...

All the latest science news on atp synthase from Phys.org. Find the latest news, advancements, and breakthroughs.

Proton pump inhibitors may be associated with pharmacovigilance signals for the occurrence of drug-induced lupus erythematosus, according to a research letter published in JAMA Dermatology. “The ...

Alternatively, variants in the genes encoding the α, β, or γ subunits of complex V may loosen coupling between the proton motive force and ATP synthesis. 13,20 In the future, it will be ...