This is not to say that antiangiogenic therapy might not be a useful tool for the treatment of glioblastoma, but at this point, evidence for the ability of these agents to augment survival is lacking.

We propose that antiangiogenic therapy can similarly stabilize vulnerable 'rupture-prone' plaques by pruning and normalizing immature intraplaque vessels, preventing further intraplaque hemorrhage.

Antiangiogenic therapy is based on the theory that blocking new blood vessel formation in tumors will stop or slow their growth. Currently, four molecular-targeted drugs are approved by the FDA ...

Obesity—which is already known to reduce survival in several types of cancer—may explain the ineffectiveness of angiogenesis inhibitors in the treatment of breast cancer. A research team led ...

Expert Commentary Since angiogenesis is virtually absent in normal adults, antiangiogenic therapy is more tumor-specific and yields a low toxicity profile. Different antiangiogenic strategies have ...

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia platforms.

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia platforms.

Antiangiogenic Therapy Escape A retrospective analysis in patients with malignant glioma who were treated with a second-line regimen containing bevacizumab after failure of treatment with an ...

But resistance to anti-angiogenic therapy limits the drugs' survival benefits. Several studies have suggested a role in the development of resistance for the immune system -- particularly innate ...

The editorial by Duda et al, entitled, “Biomarkers of Antiangiogenic Therapy: How Do We Move From Candidate Biomarkers to Valid Biomarkers?” (J Clin Oncol 10.1200/JCO.2009.24.8021) was published ...

Rush Studying Antiangiogenic Therapy To Treat Metastatic Breast Cancer Date: April 12, 2001 Source: Rush Presbyterian St. Luke's Medical Center Summary: Breast cancer researchers at Rush ...

Antiangiogenic drugs specifically block this process. This type of therapy usually has good short-term results, reducing tumor growth.