Multiplexed-engineered, iPSC-derived CAR T Cell Targets Proteins Expressed on Cancer Cells in Response to Cellular Stress and Malignant ...

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

The following is a summary of “Patient iPSC-derived neural progenitor cells display aberrant cell cycle control, p53, and DNA ...

Skeletal stem cells have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...

CTX112 is a next-generation, wholly-owned, allogeneic CAR T product candidate targeting Cluster of Differentiation 19 ... in adult patients with relapsed or refractory CD19-positive B-cell ...

The researchers also assessed the correlation between the levels of **specific immune cell types—**Cluster of Differentiation ...

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion product for B-ALL patients, is highly dependent on intrinsic features of ...

Treatment with AUTX-703 resulted in notable cell differentiation and tumor growth inhibition in various primary cancer modelsAUTX-703 IND ...

differentiation, and effector functions. Lipid Metabolism in Immune Cells: Studies on how metabolic pathways of lipid synthesis, modification, and degradation influence the function of different ...