Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan. *Corresponding Author: Max S. Wicha, Department of Internal Medicine, University of Michigan–Ann Arbor, 2800 Plymouth Road ...

CD4, CD45, CCR4, Foxp3, T-bet, RORγt, and GATA3. The Foxp3 staining buffer set (Thermo Fisher Scientific) was used for intracellular staining of Foxp3. In all staining procedures, Fc receptors were ...

Additionally, IL7R is activated by thymic stromal lymphopoietin (TSLP), which then forms a heterodimer with the TSLP receptor (TSLPR ... Inc. Immunochemical staining of mouse IL-7RA in mouse ...

For instance, only a little is known about the structure of their B cell receptor (BCR) repertoires in autoimmune disorders, including multiple sclerosis (MS), a severe neuroinflammatory disease with ...

Cells were stained for 20 min at room temperature with different combinations of fluorochrome-conjugated antibodies and dead cell stain (see Supplementary Methods ... TNBS-specific CD154+CD4+ and ...