The main cells that HIV infects are those carrying a receptor molecule called CD4 on their surface. CD4 is found on immune cells, most particularly on T-helper cells and on macrophages. HIV gets ...

Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of ...

Panel A shows a circulating leukemic hairy cell (arrow) in a peripheral-blood smear (May–Grünwald–Giemsa stain ... chimeric antigen receptor T-cell products, or T-cell–redirecting ...

These include fusion inhibitors, CCR5 inhibitors and attachment inhibitors. In order to enter a host cell, HIV must bind to two separate receptors on the cell’s surface: the CD4 receptor and a ...

The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are activated when IFN-γ binds to the IFN-γ receptor ... of malignancy. The CD4+ T helper cells and CD8+ cytotoxic ...

The absorbed antiserum specifically stained NKG2D-transfected CHO cells, but did not stain CHO cells transfected with either of the distantly related NK receptors, or untransfected control cells (Fig.

Additionally, IL7R is activated by thymic stromal lymphopoietin (TSLP), which then forms a heterodimer with the TSLP receptor (TSLPR ... Inc. Immunochemical staining of mouse IL-7RA in mouse ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...