The Golden Nugget Biloxi is situated in southeastern Biloxi, Mississippi, across the street from the Maritime and Seafood Industry Museum and within walking distance of the Ohr-O'Keefe Museum of Art.
The company owns the Golden Nugget Hotel and Casino in Las Vegas, Laughlin and Lake Tahoe, Nevada, Lake Charles, Louisiana, Biloxi, Mississippi, Atlantic City, and Cripple Creek, Colorado.