The amino acid sequence of a protein encodes its three-dimensional structure and determines its biological function. Although researchers can readily generate proteins with altered amino acid ...

Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...

The specific structure of a protein determines its unique biological function. (click on image to enlarge) (Image: National Human Genom Research Institute) Proteins are built from a set of 20 standard ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

Our brain's remarkable ability to form and store memories has long fascinated scientists, yet most of the microscopic ...

Their work suggested that this new function of RAD52 facilitates the survival of cancer cells. In the new study, Spies’ team used cryogenic electron microscopy (CryoEM) to show that RAD52 proteins ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these ...

"For the first time, we have managed to capture the full structure of native RBP3 in pigs with a resolution of 3.67 Å. This is an important step in understanding the function of this protein, ...

Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

Donado then compared the structure of Granzyme K to other proteins in the body to hypothesize its function. “I compared the structure, the protein structure Granzyme K, to the structure of all ...