The FDA approved the first generics of the direct oral anticoagulant rivaroxaban, the agency announced on Tuesday.

Two companies have received approved for a generic of the 2.5 mg tablet of anticoagulant rivaroxaban, which is used to reduce ...

Half of renally-cleared rivaroxaban is cleared as unchanged drug and half as inactive metabolites. ‡Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole ...

Rivaroxaban (Xarelto) was also associated with higher risk than apixaban (42.94 vs 20.05 per 1,000 person-years, HR 2.15, 95% CI 1.18-3.94), again with a stronger association in those using ART ...

Rivaroxaban, on the other hand, is associated with an increased signal of harm. “What our analysis shows is that within the limitations of the studies that have been done, it does appear that the risk ...

In this randomized controlled trial, abelacimab led to significantly lower rates of major or clinically relevant nonmajor ...