There is an ever-growing curiosity in the potential benefit of combining phenotypic and genomic data, in the quest to advance small-molecule drug discovery. Understanding the advantages and challenges ...

Among the hundreds of thousands of chemical compounds produced by plants, some may hold the key to treating human ailments and diseases. But recreating these complex, naturally occurring molecules in ...

Virtual screening of large compound libraries is ... and could dramatically speed up drug discovery. “When presented with enough examples drawn from conventional docking, the machine-learning ...

The traditional drug discovery process of identifying the ... “We completed a virtual screen of 6.5 billion drug-like compounds in a couple of days,” said Clayton Mellina, Chief AI Officer ...

Horizon Discovery provides ... from small virtual start-ups to multinationals. The company has developed a suite of functional genomic screening technologies, including a CRISPR-Cas9 platform.

Finding new medicines has always been a long, expensive, and complicated process. Scientists need to identify the right targets in the body, test thousands of potential compounds, and spend years in ...

Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

Virtual Screening Capabilities ... suite of ligand design and discovery services integrates cutting-edge computational methodologies with domain-specific expertise, empowering researchers and ...

“It has been incredibly hard to manipulate these types of complex plant compounds for the benefit of drug design,” says ... “The ability to now combine virtual predictions with real-world ...