Iran and the U.S., holding talks in Rome, will have experts meet to discuss details of a possible deal over Tehran's rapidly advancing nuclear program, Iran's top diplomat says.

That the talks are even happening represents a historic moment, given the decades of enmity between the two countries since the 1979 Islamic Revolution and the U.S. Embassy hostage crisis.

The foreign ministry of Oman, which is mediating the nuclear negotiations between the United States and Iran, said the two sides were seeking an agreement that guarantees the Islamic republic does not possess nuclear weapons.