For years, the strength of the 49ers was their run defense. Now it stinks. Until recently, the 49ers had gone 55 games in a ...

The 49ers lost defensive tackle Javon Hargrave early with a torn triceps. Middle linebacker Fred Warner has played with an ...

The Los Angeles Rams, Green Bay Packers, Tampa Bay Buccaneers, Seattle Seahawks and Atlanta Falcons are still in the hunt in ...

The San Francisco 49ers need to do something different offensively. Last season they were one of the best outfits in the NFL.

After the San Francisco 49ers blew multiple opportunities and committed a season-high 11 penalties in a loss to the Miami ...

On Friday this week, head coach Kyle Shanahan was asked about Purdy's harsh self-assessment.

Jake Moody's performance this season has been a frustrating storyline for many San Francisco 49ers fans. The second-year ...

San Francisco 49ers Head coach Kyle Shanahan provided updates on LB Dre Greenlaw's game status and shared a scouting report on the Detroit Lions. San Francisco 49ers TE George Kittle, QB Brock Purdy, ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters during a Monday conference call, delivering multiple injury ...

According to 49ers head coach Kyle Shanahan, LB De'Vondre Campbell refused to enter the game in the third quarter when asked ...

The 49ers have suspended linebacker De'Vondre Campbell for the rest of the season after he refused to play on Thursday night, ...