gut.bmj

Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models often fail to fully recapitulate all aspects of the human disease. A ...
IEEE

GRNNLink: Predicting gene regulatory links from single-cell RNA-seq data using graph recurrent neural network

Abstract: Single-cell RNA sequencing (scRNA-seq) technology offers unprecedented opportunities for inferring gene regulatory networks (GRNs) at the genome level. However, scRNA-seq data is highly ...
Frontiers

Tumor heterogeneity assessment using single-cell RNA sequencing (scRNA-seq): applications in lung cancer for diagnosis and treatment

Recent progress in single-cell RNA sequencing has led to mechanistic and clinically actionable insight into genetic heterogeneity and tumor progression via transcriptome profiling at single-cell level ...