BMJ1d
AB1108 ANALYSIS OF HOMOGENOUS PATTERN IN ANTI-NUCLEAR ANTIBODY-INDIRECT IMMUNOFLUORESCENCE ASSAY
Background: Autoantibodies that produce the homogenous pattern on anti-nuclear antibody-indirect immunofluorescence (ANA-IIF) assay using human epithelial cell (HEp-2) substrate are histones, dsDNA ...
BMJ1d
Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2
Correspondence to Professor Daozhang Cai and Dr Xiaochun Bai, Department of Orthopedics, Academy of Orthopedics - Guangdong Province, Orthopedic Hospital of Guangdong Province, The Third Affiliated ...
BMJ1d
Use of cell permeable NBD peptides for suppression of inflammation
Nuclear factor (NF)-κB is a ubiquitous and essential transcription factor whose dysregulation has been linked to numerous diseases including arthritis and cancer. It is therefore not surprising that ...
BMJ1d
EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update
Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials ...
BMJ1d
EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
15 Department of Radiology. Leiden University Medical Centre, Leiden, The Netherlands 16 Department of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands ...
BMJ3d
The genetic basis of spondyloarthritis
Modern technological innovations have advanced our understanding of the genetic basis of spondyloarthritis. In ankylosing spondylitis (AS), where the major histocompatibility complex (MHC) accounts ...
BMJ4d
Implementation of recommendations in rheumatic and musculoskeletal diseases: considerations for development and uptake
A clinical guideline is a document with the aim of guiding decisions based on evidence regarding diagnosis, management and treatment in specific areas of healthcare. Specific to rheumatic and ...
BMJ4d
OP0027 Abnormal B Cell Activation through Cellular Metabolic Reprogramming and Its Relevance To The Pathogenesis of SLE
Background B cells play a pivotal role in autoimmune diseases. In SLE, IFN signature is displayed and aberrant function of Toll-like receptors (TLR) for recognizing nucleic acids contributes to its ...
BMJ5d
OP0132 TREAT-TO-TARGET APPROACH ALLOWS TO INDUCE SUSTAINED CLINICAL REMISSION IN OVER 60% OF PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS
Background: Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission. However, such studies are difficult to conduct in axial ...
BMJ5d
POS0803 VUNAKIZUMAB IN ACTIVE ANKYLOSING SPONDYLITIS: A RANDOMIZED, DOUBLE-BLIND, ADAPTIVE, SEAMLESS, PHASE 2/3 STUDY
3 The First Affiliated Hospital of Guangxi Medical University, NanNing, China 4 The Second Affiliated Hospital of Guangxi Medical University, NanNing, China 5 The First Affiliated Hospital of ...
BMJ6d
AB0267 BODY COMPOSITION IN PATIENTS WITH RHEUMATOID ARTHRITIS
Background: Rheumatoid arthritis (RA) is a complex inflammatory disease that modifies body composition. Using the dual-energy x-ray absorptiometry (DXA) in RA patients could be a method for body ...
BMJ6d
POS0419 THE ROLE OF OROSOMUCOID 2 IN THE REGULATION OF BONE REMODELING BY INHIBITING OSTEOCLASTOGENESIS AND PROMOTING OSTEOGENESIS
1 Wonkwang University Medical School, Internal Medicine, Iksan, Korea, Rep. of (South Korea) 2 Jeonbuk National University Medical School, Internal Medicine, Jeonju, Korea, Rep. of (South Korea) ...