Objectives In February 2019, the Chair of the House of Commons’ Science and Technology Committee sent a letter to forty universities warning them to upload their backlog of missing summary results ...

Overdiagnosis has been described as ‘unwarranted diagnosis’ (Moynihan et al, 2018). It is the formulation and conveyance of a label –generally of a disease or condition - that can lead to patient harm ...

Objectives To determine the barriers and facilitators to using real world data (RWD) in healthcare settings in low-and middle-income countries (LMICs). Method We conducted a systematic review through ...

Scientific progress, including in evidence-based medicine, requires all available evidence to be accessed, scrutinised, interpreted and used. Missing or incomplete evidence creates biases and errors ...

Scientific progress requires transparency and openness. The ability to critique, replicate and implement scientific findings depends on the transparency of the study design and methods, and the open ...

After conducting a database search, the subsequent phase in the execution of systematic reviews (SRs) involves title and abstract screening.1 This stage bears significant importance and necessitates ...

Breast density is one of a number of independent risk factors for breast cancer.1 Having dense breasts (heterogeneously dense or extremely dense) is prevalent in 40%–50% of women in the breast ...

Having suggested that so-called ‘rapid’ reviews have been misnamed and should instead be called ‘restricted reviews’, Members of the Oxford Centre for Evidence Based Medicine now suggest ways in which ...

Changing disease or health risk definitions and labels where there is a case for no or little net benefit and significant harm, has the potential to affect millions of people worldwide. It appears, on ...

Qualitative research has an important place within evidence-based health care (EBHC), contributing to policy on patient safety and quality of care, supporting understanding of the impact of chronic ...

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, ...

Existing reporting checklists lack the specificity and comprehensiveness required to effectively guide the documentation of acupuncture case reports. Therefore, we developed a reporting guideline ...